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BI 2536 编号 : 52616

化学信息

产品英文名称BI 2536
分子式C28H39N7O3 
分子量521.65 
SmileCC[[email protected]]1C(=O)Nc2cnc(nc2N1C3CCCC3)Nc4ccc(cc4OC)C(=O)NC5CCNCC5
InChiKeyHDNJDRTZRRBORL-NRFANRHFSA-N
InChiInChI=1S/C26H35N7O3/c1-3-21-25(35)30-20-15-28-26(32-23(20)33(21)18-6-4-5-7-18)31-19-9-8-16(14-22(19)36-2)24(34)29-17-10-12-27-13-11-17/h8-9,14-15,17-18,21,27H,3-7,10-13H2,1-2H3,(H,29,34)(H,30,35)(H,28,31,32)/t21-/m0/s1
Cas755038-02-9
MDLMFCD18711693

技术数据

纯度98% 
质量控制

产品详情

BI2536 is a potent Plk1 inhibitor with IC50 of 0.83 nM, BI2536 shows 4- and 11-fold greater selectivity against Plk2 and Plk3; BI2536 also is a BRD4 inhibitor(IC50= 25 nM). 

结构

52616 - BI 2536 | CAS 755038-02-9

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