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BIO-acetoxime 编号 : 101401

化学信息

产品英文名称BIO-acetoxime
Iupac 化学名称[[2-(6-bromo-2-oxo-1H-indol-3-ylidene)indol-3-yl]amino] acetate 
同义词GSK-3 Inhibitor 
英文同义词GSK-3 Inhibitor 
分子式C18H12BrN3O3 
分子量398.21 
SmileC(C)(=O)ONC=1C(N=C2C=CC=CC12)=C1C(NC2=CC(=CC=C12)Br)=O
InChiKeyORWSYHWTBSHFIV-UHFFFAOYSA-N
InChiInChI=1S/C18H12BrN3O3/c1-9(23)25-22-16-12-4-2-3-5-13(12)20-17(16)15-11-7-6-10(19)8-14(11)21-18(15)24/h2-8,22H,1H3,(H,21,24)
Cas667463-85-6

技术数据

外观Red-brown solid 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
质量控制

产品详情

BIO-Acetoxime is a potent and selective GSK-3a/b inhibitor that reduces invasiveness of gliomas and extends animal survival in intracranial glioma models. Also, BIO-Acetoxime induces Wnt signaling and inhibits CD8+ T cell effector differentiation. 

结构

101401 - BIO-acetoxime | CAS 667463-85-6

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