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ENMD-2076 编号 : 111909

化学信息

产品英文名称ENMD-2076
Iupac 化学名称6-(4-methylpiperazin-1-yl)-N-(5-methyl-1H-pyrazol-3-yl)-2-[(E)-2-phenylethenyl]pyrimidin-4-amine 
同义词ENMD 2076; ENMD2076; cc-471 
英文同义词ENMD 2076; ENMD2076; cc-471 
分子式C21H25N7 
分子量375.47 
SmileCC1=CC(=NN1)NC2=NC(=NC(=C2)N3CCN(CC3)C)C=CC4=CC=CC=C4
InChiKeyBLQYVHBZHAISJM-UHFFFAOYSA-N
InChiInChI=1S/C21H25N7/c1-16-14-20(26-25-16)23-19-15-21(28-12-10-27(2)11-13-28)24-18(22-19)9-8-17-6-4-3-5-7-17/h3-9,14-15H,10-13H2,1-2H3,(H2,22,23,24,25,26)
Cas934353-76-1

技术数据

外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
质量控制

产品详情

ENMD-2076 has selective activity against Aurora A and Flt3 with IC50 of 14 nM and 1.86 nM, 25-fold selective for Aurora A than over Aurora B and less potent to VEGFR2/KDR and VEGFR3, FGFR1 and FGFR2 and PDGFR. 

结构

111909 - ENMD-2076 | CAS 934353-76-1

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