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Etamicastat HCl salt 编号 : 16071009

化学信息

产品英文名称Etamicastat HCl salt
Iupac 化学名称(R)-5-(2-aminoethyl)-1-(6,8-difluorochroman-3-yl)-1,3-dihydro-2H-imidazole-2-thione hydrochloride 
同义词BIA 5-453; BIA5-453 
英文同义词BIA 5-453; BIA5-453 
分子式C14H16ClF2N3OS 
分子量347.8088 
SmileCl.NCCC1=CNC(N1[[email protected]]1COC2=C(C=C(C=C2C1)F)F)=S
InChiKeyCKRDOSZCFINPAD-RFVHGSKJSA-N
InChiInChI=1S/C14H15F2N3OS.ClH/c15-9-3-8-4-11(7-20-13(8)12(16)5-9)19-10(1-2-17)6-18-14(19)21;/h3,5-6,11H,1-2,4,7,17H2,(H,18,21);1H/t11-;/m1./s1
Cas677773-32-9

技术数据

外观Solid powder 
纯度98% by HPLC 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
质量控制

产品详情

Etamicastat, also known as BIA 5-453, is a potent, reversible, peripherally selective dopamine -hydroxylase inhibitor (DBH inhibitor). Chronic dopamine ß-hydroxylase inhibition with etamicastat effectively decreases blood pressure, although does not prevent the development of hypertension in the spontaneously hypertensive rat. 

结构

16071009 - Etamicastat HCl salt | CAS 677773-32-9

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