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GDC-0941 编号 : 120115

化学信息

产品英文名称GDC-0941
Iupac 化学名称4-(2-(1H-indazol-4-yl)-6-((4-(methylsulfonyl)piperazin-1-yl)methyl)thieno[3,2-d]pyrimidin-4-yl)morpholine 
同义词GDC 0941; GDC0941; RG7321; RG-7321; RG 7321; GNE0941; GNE-0941; GNE 0941; Pictrelisib 
英文同义词GDC 0941; GDC0941; RG7321; RG-7321; RG 7321; GNE0941; GNE-0941; GNE 0941; Pictrelisib 
分子式C23H27N7O3S2 
分子量513.636 
SmileCS(=O)(=O)N1CCN(CC1)CC2=CC3=C(S2)C(=NC(=N3)C4=C5C=NNC5=CC=C4)N6CCOCC6
InChiKeyLHNIIDJUOCFXAP-UHFFFAOYSA-N
InChiInChI=1S/C23H27N7O3S2/c1-35(31,32)30-7-5-28(6-8-30)15-16-13-20-21(34-16)23(29-9-11-33-12-10-29)26-22(25-20)17-3-2-4-19-18(17)14-24-27-19/h2-4,13-14H,5-12,15H2,1H3,(H,24,27)
Cas957054-30-7

技术数据

外观Solid powder 
纯度98% 
可溶性Soluble in DMSO 
存储-20 ºC for 3 years 
运输条件Shipped under ambient temperature 
质量控制

产品详情

GDC-0941 is a potent inhibitor of PI3K/ with IC50 of 3 nM, with modest selectivity against p110 (11-fold) and p110 (25-fold). 

结构

120115 - GDC-0941 | CAS 957054-30-7

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