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Luliconazole 编号 : 16123038

化学信息

产品英文名称Luliconazole
Iupac 化学名称Luliconazole 
同义词NND502; NND 502; NND502; PR2699; PR 2699; PR2699; Luzu; Lulicon 
英文同义词NND502; NND 502; NND502; PR2699; PR 2699; PR2699; Luzu; Lulicon 
分子式C14H9Cl2N3S2 
分子量354.28 
Smilec1cc(c(cc1Cl)Cl)[[email protected]@H]2CS/C(=C(/C#N)\n3ccnc3)/S2
InChiKeyYTAOBBFIOAEMLL-REQDGWNSSA-N
InChiInChI=1S/C14H9Cl2N3S2/c15-9-1-2-10(11(16)5-9)13-7-20-14(21-13)12(6-17)19-4-3-18-8-19/h1-5,8,13H,7H2/b14-12+/t13-/m0/s1
Cas187164-19-8
MDLMFCD00953915

技术数据

外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
质量控制

产品详情

Luliconazole is an azole antifungal drug. As a 1% topical cream, luliconazole is indicated for the treatment of athlete's foot, jock itch, and ringworm caused by Trichophyton rubrum and Epidermophyton floccosum. Luliconazole is an antifungal that belongs to the azole class. Although the exact mechanism of action against dermatophytes is unknown, luliconazole appears to inhibit ergosterol synthesis by inhibiting the enzyme lanosterol demethylase. Inhibition of this enzyme's activity by azoles results in decreased amounts of ergosterol, a constituent of fungal cell membranes, and a corresponding accumulation of lanosterol. (copies from http://www.rxlist.com/luzu-drug/clinical-pharmacology.htm). 

结构

16123038 - Luliconazole | CAS 187164-19-8

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