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Lys05 编号 : 16123043

化学信息

产品英文名称Lys05
Iupac 化学名称Lys05 
同义词Lys-05; Lys 05 
英文同义词Lys-05; Lys 05 
分子式C23H23Cl2N5 
分子量440.372 
InChiKey
InChi
Cas1391426-22-4

技术数据

外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
质量控制

产品详情

Lys05 is a potent lysosomal autophagy inhibitor. Lys05 is a previously undescribed dimeric chloroquine which more potently accumulates in the lysosome and blocks autophagy compared with HCQ. Lys05 produced more potent antitumor activity as a single agent both in vitro and in vivo in multiple human cancer cell lines and xenograft models compared with HCQ. Lys05 is therefore a new lysosomal autophagy inhibitor that has potential to be developed further into a drug for cancer and other medical applications. 

结构

16123043 - Lys05 | CAS 1391426-22-4

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