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RU-SKI 43 编号 : 6111503

化学信息

产品英文名称RU-SKI 43
Iupac 化学名称RU-SKI 43 
同义词RU-SKI43; Hhat Inhibitor 
英文同义词RU-SKI43; Hhat Inhibitor 
分子式C22H30N2O2S 
分子量386.55 
InChiKey
InChi
Cas1043797-53-0

技术数据

外观crystalline solid 
纯度98% 
可溶性Soluble in DMSO 
存储3 years -20ºCpowder 
运输条件Shipped under ambient temperature as non-hazardous chemical. 
质量控制

产品详情

RU-SKI 43 is a small molecule inhibitor of Hhat(Hedgehog acyltransferase), the enzyme responsible for the attachment of palmitate onto Shh.


RU-SKI 43 reduced pancreatic cancer cell proliferation and Gli-1 activation through Smoothened-independent non-canonical signaling. In addition, RU-SKI 43 treatment inhibited two key proliferative pathways regulated by Akt and mTOR.


 

结构

6111503 - RU-SKI 43 | CAS 1043797-53-0

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